Yu Ra Jung • Sue Jeong Kim • Kyung Cheol Sohn • Young Lee • Young Joon Seo • Young Ho Lee • Kyu Uang Whang • Chang Deok Kim • Jeung Hoon Lee • Myung Im
Abstract
eLight-emitting diodes (LED) have been used to treat acne vulgaris. However, the efficacy of LED on sebaceous lipid production in vitro has not been examined. This study investigated the efficacy of 415 nm blue light and 630 nm red light on lipid production in human sebocytes. When applied to human primary sebocytes, 415 nm blue light suppressed cell proliferation. Based on a lipogenesis study using Oil Red O, Nile red staining, and thinlayered chromatography, 630 nm red light strongly downregulated lipid production in sebocytes. These results suggest that 415 nm blue light and 630 nm red light influence lipid production in human sebocytes and have beneficial effects on acne by suppressing sebum production.
Keywords
Acne LED Sebocyte Sebum